3-oxoadipate enol-lactonase (EC 3.1.1.24) is an enzyme that catalyzes the reaction
The enzyme characterised from Pseudomonas putida hydrolyses the enol lactone, 5-oxo-4,5-dihydro-2-furylacetic acid, to β-ketoadipic acid.The reaction is part of a pathway that breaks down the antioxidant, protocatechuic acid, and other aromatic compounds.
This enzyme is a hydrolase, specifically one acting on carboxylic ester bonds. The systematic name is 4-carboxymethylbut-3-en-4-olide enol-lactonohydrolase. Other names in common use include carboxymethylbutenolide lactonase, β-ketoadipic enol-lactone hydrolase, 3-ketoadipate enol-lactonase, 3-oxoadipic enol-lactone hydrolase, and β-ketoadipate enol-lactone hydrolase.
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