(Iso)eugenol O-methyltransferase () is an enzyme that catalyzes the chemical reaction
This is a methylation reaction in which isoeugenol is converted to its di-ether, methyl isoeugenol. The methyl group comes from the cofactor, S-adenosyl methionine (SAM), which becomes S-adenosyl-L-homocysteine (SAH). The enzyme was characterised from Clarkia breweri.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:isoeugenol O-methyltransferase. It also acts on eugenol
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