DXD can refer to:
Destruction By Definition, ska-core band The Suicide Machines' first album. Digital by Digital, a section of the Cinequest Film Festival's competition Digital eXtreme Definition, a professional audio format. Disney Xtreme Digital, a community web site by Disney, similar to MySpace Disney XD, the Disney channel that replaced Toon Disney. Drag x Drive, a video game for Nintendo Switch 2. High School DxD, a Japanese light novel series written by Ichiei Ishibumi.