Wissahickon may refer to the following in the U.S. state of Pennsylvania:

Wissahickon, Philadelphia, a section or neighborhood of Philadelphia Wissahickon Creek, a tributary of the Schuylkill River Wissahickon Memorial Bridge, spans the above creek in Philadelphia Wissahickon Trail, a suburban trail Wissahickon Formation, a mapped bedrock unit in Pennsylvania, New Jersey, and Delaware Wissahickon High School, in the borough of Ambler Wissahickon (house), a historic apartment building in Philadelphia Wissahickon School District, in Montgomery County Wissahickon (SEPTA station), a passenger rail station in Northwest Philadelphia Wissahickon Transportation Center, a bus station next to the rail station Wissahickon Skating Club, a non-profit skating club in the Chestnut Hill section of Philadelphia Wissahickon Valley Park, formerly part of Fairmount Park in Philadelphia USRC Wissahickon (1904), one of two Winnisimmet-class harbor tugs Saul High School of Agricultural Sciences, formerly known as the Wissahickon Farm School

See also USS Wissahickon, disambiguation