Nughedu San Nicolò () is a village and comune (municipality) in the Metropolitan City of Sassari in the autonomous island region of Sardinia in Italy, located about northwest of Cagliari and about southeast of Sassari. It has 710 inhabitants.

Nughedu San Nicolò borders the municipalities of Anela, Bono, Bonorva, Bultei, Ittireddu, Ozieri, and Pattada.

Demographics As of 2026, the population is 710, of which 51.3% are male, and 48.7% are female. Minors make up 8.7% of the population, and seniors make up 34.6%.

Immigration As of 2025, immigrants make up 5.0% of the population. The 5 largest foreign countries of birth are Romania, Albania, Argentina, France, and Austria.

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