Senator Lewis may refer to:
Members of the United States Senate Dixon Hall Lewis (1802–1848), U.S. Senator from Alabama from 1844 to 1848 J. Hamilton Lewis (1863–1939), U.S. Senator from Illinois from 1913 to 1919 and again from 1931 to 1939 John F. Lewis (1818–1895), U.S. Senator from Virginia 1870 to 1875
United States state senate members Albert B. Lewis (1925–2021), New York State Senate Bob Lewis (Washington politician) (1925–2015), Washington State Senate Bonnie Titcomb Lewis, Maine State Senate Brian J. Lewis (born 1929), Washington State Senate Dave Lewis (politician) (born 1942), Montana State Senate David John Lewis (1869–1952), Maryland State Senate Earl Ramage Lewis (1887–1956), Ohio State Senate Frank Lewis (Nebraska politician) (born 1939), Nebraska State Senate Gerald Lewis (politician) (1934–2022), Florida State Senate H. Craig Lewis (1944–2013), Pennsylvania State Senate Helmar Lewis (1900–1999), Wisconsin State Senate James T. Lewis (1819–1904), Wisconsin State Senate James Lewis (Indiana politician) (1930–2016), Indiana State Senate Jason Lewis (Massachusetts politician) (born 1968), Massachusetts State Senate Jerry Lewis (Arizona politician) (born 1956), Arizona State Senate John W. Lewis Jr. (1906–1977), Illinois State Senate John Lewis (California politician) (born 1954), California State Senate Loran L. Lewis (1825–1916), New York State Senate Morgan Lewis (governor) (1754–1844), New York State Senate Patty Lewis (fl. 2020s), Missouri State Senate Phil Lewis (Florida politician) (1929–2012), Florida State Senate Robert S. Lewis (1856–1956), North Dakota State Senate Seth Lewis (fl. 2020s), Illinois State Senate Thomas Lewis (Kentucky politician) (1749–1809), Kentucky State Senate Tom Lewis (American politician) (1924–2003), Florida State Senate William Lewis (New York politician) (1827–1891), New York State Senate
Other John Wood Lewis Sr. (1801–1865), Confederate States Senator from Georgia from 1862 to 1863