Shoot to kill may refer to:

Law Deadly force, a general concept in the theory of self-defence (where "shooting to kill" is aiming one's shots with the specific intention of causing fatal injury) Operation Kratos, a set of tactics by the Metropolitan Police Service of London to kill suspected terrorists Postenpflicht, a general order at Nazi concentration camps requiring guards to shoot to kill Schießbefehl, an order given to border guards in East Germany between 1960 and 1989, directing them to use lethal force against anyone trying to cross the inner German border Shoot-to-kill policy in Northern Ireland, under which suspects were alleged to have been deliberately killed without any attempt to arrest them

Film and TV Shoot to Kill (1947 film), a black-and-white film noir Shoot to Kill (1960 film), a British crime film directed by Michael Winner Shoot to Kill (1988 film), an adventure thriller film starring Sidney Poitier Shoot to Kill (1990 film), a drama-documentary on the actions of the police in Northern Ireland "Shoot to Kill" (Between the Lines), a 1994 television episode

Music Shoot to Kill, a mixtape by rapper Mickey Avalon Shoot to Kill (G-Unit album), an album by G-Unit eventually released as T.O.S: Terminate on Sight Shoot to Kill (X-Pistols album), a 2011 album by X-Pistols

Other Shoot to Kill (novel), a 2014 novel by Steve Cole Final Boss (Halo team), professional Halo team founded as Shoot to Kill (StK)