M107 most often refers to: XM107/M107 Barrett rifle, a semi-automatic .50 caliber rifle M107 (projectile), a 155 mm projectile used by the United States Army M107 self-propelled gun, an American 175 mm self-propelled gun

M107 may also refer to:

Military German minesweeper M 107 HMS Pembroke (M107), a British Royal Navy minehunter M107 bomb; see M47 bomb

Other uses M-107 (Michigan highway), a former state highway in Michigan M107 (New York City bus), a bus route in Manhattan, New York City Irem M-107, an arcade system board Messier 107, a globular cluster in the constellation Ophiuchus the initial designation of the Soviet Klimov VK-107 aircraft engine