Cardinal of Guise can refer to these members of the French ducal family de Guise who became cardinals: Louis I, Cardinal of Guise (1527–1578), Bishop of Troyes Louis II, Cardinal of Guise, (1555–1588), nephew of Louis I Louis III, Cardinal of Guise, (1575–1621), the third son of Henry I, Duke of Guise, and Catherine of Cleves

See also Cardinal of Lorraine (disambiguation)