Twitchell (also spelled Twichell) is a surname, and may refer to:
Chase Twichell, American poet Jenny Twitchell Kempton (1835–1921), American operatic contralto Rev. Dr. Joseph Twichell, New England reverend, friend of Mark Twain Karl Twitchell, American engineer and surveyor Kent Twitchell, American artist Mark Twitchell, Canadian filmmaker convicted of murder Marshall H. Twitchell, Louisiana state senator and carpetbagger during the Reconstruction Era in the United States Paul Twitchell, American religious leader Ralph Twitchell, American architect Wayne Twitchell, American baseball player
See also Twitchell Reservoir, in California Twitchell Creek, in New York Twitchell Lake (disambiguation) Twitchell Mountain, in New York Twitchett Twichell, a dialect term for an alley Commonwealth v. Twitchell