Tetrapolis ( '(having) four cities') may refer to:

Tetrapolis (Attica), a district comprising four cities in ancient Attica, Greece Doric Tetrapolis, a group of four cities in ancient Doris, Greece Syrian Tetrapolis, a region of the Seleucid Empire Antioch by itself was also sometimes called Tetrapolis Kibyran Tetrapolis in Lycia, see Kibyra