Isker may refer to:
People Abder Isker (1920–2010), French Algerian film director, great-uncle of Akim Isker Akim Isker (born 1978), French Algerian film director and actor
Places Îsker, the Siberian Tatar name for Qashliq, a medieval Siberian Tatar city Isker River, an alternative spelling of the Iskar River in Bulgaria