Route 431, or Highway 431, may refer to:
Canada Newfoundland and Labrador Route 431
Cuba
Callejero de Reparto Universitario (4–431)
Hungary Main road 431 (Hungary)
India National Highway 431 (India)
Israel Highway 431 (Israel)
Japan Japan National Route 431
United States U.S. Route 431 Florida: Florida State Road 431 Florida State Road 431B (former) County Road 431 (Seminole County, Florida) County Road 431B (Seminole County, Florida) Indiana State Road 431 (former) Iowa Highway 431 (former) Nevada State Route 431 New York State Route 431 Puerto Rico Highway 431 Tennessee State Route 431 Texas: Texas State Highway Loop 431 Farm to Market Road 431 Washington State Route 431 Wyoming Highway 431