Edward McGuire may refer to:

Eddie McGuire (born 1964), Australian television personality Edward McGuire (painter) (1932–1986), Irish artist Edward McGuire (composer) (born 1948), British composer Edward McGuire (politician) (1901–1992), Irish politician and tennis player E. J. McGuire (Edward John McGuire, 1952–2011), ice hockey coach Teddy McGuire, Scottish footballer