Hyperdynamic circulation is abnormally increased circulatory volume. Systemic vasodilation and the associated decrease in peripheral vascular resistance results in decreased pulmonary capillary wedge pressure and decreased blood pressure, presenting usually with a collapsing pulse, but sometimes a bounding pulse. In effort to compensate the heart will increase cardiac output and heart rate, which accounts for the increased pulse pressure and sinus tachycardia.Mosby's Medical Dictionary, 8th edition. S.v. "hyperdynamic circulation." Retrieved July 28, 2010 from http://medical-dictionary.thefreedictionary.com/hyperdynamic+circulation Hyperdynamic circulation is a hallmark of distributive shock (such as sepsis) and physiological states like normal pregnancy.Cecconi M, Evans L, Levy M, Rhodes A. Sepsis and septic shock. Lancet. 2018 Jul 7;392(10141):75-87. doi: 10.1016/S0140-6736(18)30696-9. PMID: 29937192.Valensise H, et al. Maternal Hemodynamics from Preconception to Delivery... J Clin Med. 2024. PMID: 38350640. It is also a defining feature of high-output cardiac states, which include severe anemia, hyperthyroidism, liver cirrhosis, and large arteriovenous malformations.Sonaglioni A, et al. Heart Failure with Supranormal Ejection Fraction... J Clin Med. 2025. PMID: 42513274. __TOC__ Possible causes
Kidney disease Hypovolemia Adrenal crisis - especially after fluid replacementBonachour et al. Hemodynamic changes in acute adrenal insufficiency. Intensive Care Medicine (1994) 20:138-141 Anemia Anxiety Aortic RegurgitationSattar, Hussain A. Pathoma: Fundamentals of Pathology. Pathoma LLC (2011); p. 80. AV fistulae Beriberi Dysautonomia Erythroderma Exercise Liver failure HydrocephalusGreitz, Dan. Radiological Assessment of hydrocephalus: new theories and implications for therapy. Neurosurg Rev (2004) 27: 145-165. Hypercapnia Paget's disease Portal hypertension Pregnancy Pyrexia Thyrotoxicosis Vasodilator drugs
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