Pliskin is a Jewish locational surname, which originally meant a person from the villages of Pliski, Belarus or Pliszki, Poland.Dictionary of American Family Names. "Pliskin Family History", Oxford University Press, 2013. Retrieved on 18 January 2016. Notable people with the surname include:

Joseph Pliskin (born 1947), Israeli health researcher Zelig Pliskin (born 1946), American rabbi and writer Iroquois Pliskin, fictional character in the Metal Gear series

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