SPM may refer to:

Places Saint Pierre and Miquelon (ISO 3166-1 code), an overseas French territory Salón de la Plástica Mexicana, an art museum in Mexico City Salsali Private Museum, Dubai, UAE Shyama Prasad Mukherji College, University of Delhi, India St Philip's Marsh depot, Bristol, UK, rail depot code

Organizations Socialist Party of Canada (Manitoba) Socialist Party of Macedonia Somali Patriotic Movement Sociedade Portuguesa de Matemática, the Portuguese Mathematical Society Porzellanfabrik Siegmund Paul Meyer, a former German porcelain manufacturer between 1899 and 2019

Science and computing Scanning probe microscopy Scratchpad memory, in computing Self-phase modulation, nonlinear light–matter interaction Specialized proresolving mediators, cell signaling molecules Standard Progressive Matrices (IQ test) Suspended particulate matter

Software Statistical parametric mapping of brain activity

Business and industry Supplier performance management Single-point mooring, for tankers S.P.M. Publications, later Key Publications, was an American comic-book company founded by Stanley P. Morse

People South Park Mexican, aka SPM, American rapper S. P. Muthuraman, Indian film director Sean Patrick Maloney, American politician.

Other Akukem language (ISO 639:spm), a Ramu language of Papua New Guinea IPCC Summary for Policymakers Sijil Pelajaran Malaysia (Malaysian Certificate of Education), a standardized test for secondary students in Malaysia Super Paper Mario, a video game for the Wii Spangdahlem Air Base, is a NATO air base and located near the small German town of Spangdahlem