Route 105 or Highway 105 may refer to:
Argentina National Route 105 La Pampa Provincial Route 105
Canada New Brunswick Route 105 Nova Scotia Highway 105 (Trans-Canada Highway) Ontario Highway 105 Prince Edward Island Route 105 Quebec Route 105
China China National Highway 105 S105 Nansha Port Expressway (Guangdong)
Costa Rica National Route 105
India National Highway 105 (India)
Japan Route 105 (Japan)
Nigeria F105 highway (Nigeria)
Philippines N105 highway (Philippines)
South Korea Namhae Expressway Branch 3
United Kingdom road B105 road
United States Interstate 105 (multiple highways) Alabama State Route 105 Arkansas Highway 105 Colorado State Highway 105 Florida State Road 105 Georgia State Route 105 Georgia State Route 105 (1932–1937) (former) Illinois Route 105 Indiana State Road 105 Iowa Highway 105 (former) County Road 105 (Mitchell County, Iowa) County Road 105 (Worth County, Iowa) K-105 (Kansas highway) Kentucky Route 105 Louisiana Highway 105 Louisiana State Route 105 (former) Maine State Route 105 Maryland Route 105 (former) Massachusetts Route 105 M-105 (Michigan highway) (former) Minnesota State Highway 105 Missouri Route 105 Nebraska Highway 105 County Route 105 (Bergen County, New Jersey) County Route 105 (Ocean County, New Jersey) New Mexico State Road 105 New York State Route 105 County Route 105 (Dutchess County, New York) County Route 105 (Erie County, New York) County Route 105 (Montgomery County, New York) County Route 105 (Nassau County, New York) County Route 105 (Niagara County, New York) County Route 105 (Onondaga County, New York) County Route 105 (Orange County, New York) County Route 105 (Seneca County, New York) County Route 105 (Steuben County, New York) County Route 105 (Suffolk County, New York) County Route 105 (Sullivan County, New York) County Route 105A (Sullivan County, New York) County Route 105 (Tompkins County, New York) North Carolina Highway 105 Ohio State Route 105 Oklahoma State Highway 105 Pennsylvania Route 105 (former) South Carolina Highway 105 South Dakota Highway 105 (former) Tennessee State Route 105 Texas State Highway 105 Texas State Highway Loop 105 Texas State Highway Spur 105 (former) Farm to Market Road 105 Utah State Route 105 Vermont Route 105 Vermont Route 105A Virginia State Route 105 Washington State Route 105 West Virginia Route 105 Wisconsin Highway 105
Territories Puerto Rico Highway 105
See also A105 B105 road D105 road P105 R105 road (Ireland)