F27 or F-27 may refer to: F-27 Sport Cruiser, a trimaran sailboat design Fokker F27 Friendship, a 1955 Dutch turboprop airliner Fairchild F-27, a 1958 American variant of the turboprop airliner HMS Lynx (F27), a 1955 British Royal Navy Leopard-class Type 41 anti aircraft frigate Fluorine-27 (F-27 or 27F), an isotope of fluorine