Picardo is an Italian surname, meaning a person from Picardy, a historical region and cultural area of France. Notable people with the surname include:
Fabian Picardo (born 1972), Gibraltarian politician and barrister José Luis Picardo (born 1919), Spanish architect, muralist, draughtsman and illustrator Robert Picardo (born 1953), American actor and singer
See also
Picardo Farm, in Wedgwood, Seattle, Washington