Monomachos (), or in Latin Monomachus, in Ukrainian and Russian Мономах (Monomakh), is a Greek epithet, meaning "he who fights alone" and "gladiator".

It applies specifically to:

Monomachos (Byzantine family), a family of Byzantine officials Niketas Monomachos, Byzantine official and saint Constantine IX Monomachos, Byzantine emperor (r. 1042–1055) Theodosios Monomachos, nephew of the above, Byzantine official and usurper Michael Monomachos, 14th-century Byzantine general Vladimir II Monomakh, Rus' Grand Prince (r. 1113–1125) Monomakhovichi, the dynasty founded by him Hannibal Monomachus, a friend and staff officer of the Carthaginian general Hannibal

See also Monomakh's Cap, a symbol-crown of the Russian autocracy Monomachus Crown, a set of pieces of engraved Byzantine goldwork