Desu or DESU may refer to:
Desu (Japanese: です), the polite form of the Japanese copula often translated as "to be" Suiseiseki, a character from the anime and manga series Rozen Maiden whose overusage and unusual pronunciation of the copula became an early Internet meme DeSu7, an upcoming Bengali romantic action drama film Adalbert Deșu (Béla Dezső, 1909–1937), a Romanian football striker Delaware State University, sometimes abbreviated as DESU Diplôme d'études supérieures universitaires (DESU), a French academic grade