Double Up may refer to:
Music Double Up (Mase album), 1999 Double Up (R. Kelly album), 2007 "Double Up" (R. Kelly song), the title song, featuring Snoop Dogg "Double Up" (Nipsey Hussle song)
Television Double Up (Canadian game show), a 1974 quiz show Double Up (American game show), a 1992 dating game show Pinoy Big Brother: Double Up, the 2009 third season of the Filipino reality TV series Pinoy Big Brother
Other uses Double Up (sculpture), a public artwork, by Clement Meadmore, in Wisconsin, U.S. Generally refers to putting out a runner in baseball who had to tag up
Other uses Double up, a roller coaster element