Effingham may refer to:

Geography Europe Effingham, Surrey, England Effingham Hundred, a hundred in Surrey that includes the village of Effingham Effingham Junction railway station, a station near the village

North America Effingham, Ontario, Canada Effingham, Illinois, US Effingham, Kansas, US Effingham, New Hampshire, US Effingham, South Carolina, US Effingham County, Georgia, US Effingham County, Illinois, US

Ships HMS Effingham (D98), a Hawkins class heavy cruiser

Other uses Effingham (Aden, Virginia), a historic home and national historic district

See also Earl of Effingham "Effington", a song by Ben Folds from his 2008 album Way to Normal mistakenly named for the Illinois town Manci Howard, Lady Howard of Effingham