John Hemphill may refer to:
John A. Hemphill (1927-2021), United States Army general John Hemphill (actor) (born 1953), Canadian comic actor, writer, and producer John Hemphill (Texas politician) (1803–1862), American politician and judge John J. Hemphill (1849–1912), American politician from South Carolina John M. Hemphill (1892-1957), American politician from Pennsylvania