Barbara Bush (1925–2018) was the wife of George H. W. Bush and the mother of George W. Bush.

Barbara Bush may also refer to:

Barbara Bush (born 1981), daughter of George W. Bush Barbara Bush (diver) (born 1964), Canadian Olympic diver Barbara Tyson (born 1964), Canadian actress who has used the name Barbara Bush in her early career Cathy Dingman (born 1970), American professional wrestler who used the ring name Barbara Bush

See also Barbara Rush (1927–2024), American actress Barbara Bush Middle School (Irving, Texas)