Wesco is an unincorporated community in southwest Crawford County, Missouri, United States. It is located on the Meramec River, approximately eight miles southwest of Steelville.Missouri Atlas & Gazetteer, DeLorme, 1998, First edition, p. 47
Wesco was first named Wilson's Mills, after James Wilson, the proprietor of a local mill. A post office called Wilsons Mills was established in 1877, and the name was changed to Wesco in 1907. The present name is a contraction of the Western Electric Supply Company, a telephone utility.
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