Sf5 or variation may refer to:

Disulfur decafluoride (S2F10), a chemical reductively rendered as "SF5" (monosulfur pentafluoride) Pentafluorosulfate(IV) (), an anionic chemical compound Street Fighter V, a fighting video game CASA SF-5, Spanish-built license production variants of the Northrup F-5 Tiger II Freedom Fighter jet fighter Sablatnig SF-5, German WWI reconnaissance seaplane , U.S. Navy Barracuda-class submarine SF Motors SF5, an electric sport utility sedan Sf5 glass

See also SF (disambiguation)