The Confederation of Workers of Colombia (Spanish: Confederación de Trabajadores de Colombia, CTC) is a trade union centre in Colombia. It was formed in 1936,American Center for International Labor Solidarity (2006), Justice For All: The Struggle for Worker Rights in Colombia , p10 and is affiliated to the International Trade Union Confederation.

In 1976 José Raquel Mercado, a former president of CTC, was assassinated by the M-19 movement.

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