Perthes is the name of three communes in France:
Perthes, Ardennes, in the Ardennes département Perthes, Haute-Marne, in the Haute-Marne département Perthes, Seine-et-Marne, in the Seine-et-Marne département
As a German surname: Friedrich Christoph Perthes (1772–1843); publisher Georg Perthes (1869–1927); surgeon Justus Perthes (1749–1816); publisher, uncle of Friedrich Christoph Perthes
It may also refer to: Perthes-lès-Brienne, in the Aube département Perthes test, clinical test, done in surgery
See also Legg–Calvé–Perthes disease