NPHS is an initialism which may stand for:
National Public Health Service, A government health organisation in Wales.
U.S. High schools North Port High School, a public high school in North Port, Florida New Paltz High School, a public high school in New Paltz, New York New Philadelphia High School, a public high school in New Philadelphia, Ohio New Providence High School, a public high school in New Providence, New Jersey Newbury Park High School, a public school in Newbury Park, California North Penn High School, a public high school in Towamencin Township, Pennsylvania North Point High School, a public high school in Waldorf, Maryland North Pole High School, a public high school in North Pole, Alaska North Providence High School, a public high school in North Providence, Rhode Island North Pitt High School, a public high school near Bethel, North Carolina