Upham is a surname, and may refer to

Alexander Upham (1802–1841), farmer, merchant, ship builder and political figure in Nova Scotia, Canada Alfred H. Upham (1877–1945), president of Miami University from 1928 Alonzo S. Upham (1811–1882), New York politician Bill Upham (1888–1959), American baseball player Calvin H. Upham (1828–1892), American politician in Wisconsin Charles Upham (1908–1994), New Zealand soldier, most decorated Commonwealth soldier in WW2 Charles W. Upham (1802–1875), historian and U.S. Representative from Massachusetts Daniel Phillips Upham (1832–1882), Republican politician and Arkansas State Militia commander Don A. J. Upham (1809–1877), American lawyer and Wisconsin politician Edward Upham (1776–1834), antiquarian and orientalist Ernest Upham (1873–1935), New Zealand cricketer Frank B. Upham (1872–1939), U.S. Navy admiral George B. Upham (1768–1848), U.S. Representative from New Hampshire Jabez Upham (1764–1811), U.S. Representative from Massachusetts John Upham (born 1941), American baseball player Joshua Upham (1741–1808), American lawyer who became a judge and political figure in New Brunswick, Canada Misty Upham (1982–2014), Native American actress Nathaniel Gookin Upham (1801–1868), American jurist and president of the Concord and Montreal Railroad Nathaniel Upham (1774–1829), U.S. Representative from New Hampshire Oscar J. Upham (1871–1949), U.S. Marine, Medal of Honor recipient Richard Upham (1716 – c. 1775), political figure in Nova Scotia, Canada Samuel C. Upham (1819–1885), American journalist and counterfeiter of Confederate money Steadman Upham (1949–2017), American anthropologist, University of Tulsa president Thomas Cogswell Upham (1799–1872), American philosopher and educator Timothy Upham (1783–1855), American soldier in the War of 1812, subsequently collector of customs and politician Warren Upham (1850–1934), American geologist, archaeologist and librarian William Upham (1792–1853), U.S. Senator from Vermont William H. Upham (1841–1924), U.S. Army major, businessman and governor of Wisconsin

See also Upham (disambiguation)