Mark Murphy may refer to:

Sports Mark Murphy (American football executive) (born 1955), American football executive, former player at defensive back for the Washington Redskins Mark Murphy (ice hockey) (born 1976), American ice hockey player who plays for the DEG Metro Stars Mark Murphy (safety, born 1958) (born 1958), American former football player for the Green Bay Packers

Other Mark Murphy (singer) (1932–2015), American jazz singer Mark Murphy (author), author and expert on organizational leadership and employee engagement Mark Murphy (politician), member of the New Mexico House of Representatives Mark C. Murphy (born 1968), American philosopher

See also Marc Murphy (disambiguation)