Saltillo may refer to one of the following:

Places

Belize Saltillo, Belize

Mexico Saltillo, Coahuila, state capital Saltillo, a town in Las Margaritas, Chiapas

United States Saltillo, Indiana, a town Saltillo, Mississippi, a town Saltillo, Nebraska, unincorporated community Saltillo, Ohio, a village Saltillo, Pennsylvania, a borough Saltillo, Tennessee, a town Saltillo, Texas, an unincorporated community Saltillo (Adjuntas), a barrio of Adjuntas, Puerto Rico Saltillo, Arkansas, a town

Other uses Saltillo (linguistics), a name given to the glottal stop consonant in Mexican linguistics Saltillo affair, a scandal involving the Portuguese national football team during the 1986 FIFA World Cup in Mexico Saltillo tile, a terra-cotta tile originating in Saltillo, Mexico

Musicians Menton J. Matthews III, an American multi-instrumentalist known by the stage name Saltillo