CA1, CA-1, CA 1, or Ca.1 may refer to:

Aircraft and other vehicles Buhl CA-1 Airster, an American sports airplane Caproni Ca.1 (1910), an experimental biplane of 1910 Caproni Ca.1 (1914), a World War I bomber Schneider CA1, the first French tank

Biology CA1 (gene), a human gene CA1, a hippocampal subfield

Law United States Court of Appeals for the First Circuit

Places and roads the road designation for the Central American Highway 1 (CA-1), the portion of the Pan-American Highway passing through the Central American countries California State Route 1

Politics California's 1st congressional district