The 2001 NCAA Division I men's basketball tournament involved 65 schools playing in single-elimination play to determine the national champion of men's NCAA Division I college basketball for the 2000–01 NCAA Division I men's basketball season. The 63rd annual edition of the tournament began on March 13, 2001, with the play-in game, and ended with the championship game on April 2, 2001, in Minneapolis, Minnesota, at the Hubert H. Humphrey Metrodome. This was the last Final Four to be held in the Hubert H. Humphrey Metrodome, as it was demolished in 2014. A total of 64 games were played.

This tournament is the first to feature 65 teams, due to the Mountain West Conference receiving an automatic bid for the first time. This meant that 31 conferences would have automatic bids to the tournament. The NCAA decided to maintain 34 at-large bids, which necessitated a play-in game between the #64 and #65 ranked teams, with the winner playing against a #1 seed in the first round. (Another option would have been to reduce the number of at-large bids to 33, which was the option chosen for the women's tournament.) This is also the first tournament to have been broadcast in high-definition, being broadcast on CBS.

This was the last tournament where the first- and second-round sites were tied to specific regionals. The "pod system" was instituted for the 2002 tournament to keep as many teams as possible closer to their campus in the first two rounds.

The Final Four consisted of Duke, making their second appearance in the Final Four in three years, Maryland, making their first appearance, Michigan State, the defending national champions, and Arizona, making their first appearance since winning the national championship in 1997.

Duke defeated Arizona 82–72 in the national championship game to win their third national title and first since 1992. Shane Battier of Duke was named the tournament's Most Outstanding Player.

Schedule and venues

The following are the sites that were selected to host each round of the 2001 tournament:

Opening Round March 13 University of Dayton Arena, Dayton, Ohio (Host: University of Dayton)

First and Second Rounds March 15 and 17 East Region Greensboro Coliseum, Greensboro, North Carolina (Host: Atlantic Coast Conference) Nassau Veterans Memorial Coliseum, Uniondale, New York (Hosts: Hofstra University, America East Conference) West Region BSU Pavilion, Boise, Idaho (Host: Boise State University) Cox Arena, San Diego, California (Host: San Diego State University) March 16 and 18 Midwest Region University of Dayton Arena, Dayton, Ohio (Host: University of Dayton) Kemper Arena, Kansas City, Missouri (Host: Big 12 Conference) South Region Memphis Pyramid, Memphis, Tennessee (Host: University of Memphis) Louisiana Superdome, New Orleans, Louisiana (Hosts: Sun Belt Conference, University of New Orleans)

Regional semifinals and finals (Sweet Sixteen and Elite Eight) March 22 and 24 East Regional, First Union Center, Philadelphia, Pennsylvania (Host: Atlantic 10 Conference) West Regional, Arrowhead Pond of Anaheim, Anaheim, California (Host: Big West Conference) March 23 and 25 Midwest Regional, Alamodome, San Antonio, Texas (Host: University of Texas at San Antonio) South Regional, Georgia Dome, Atlanta, Georgia (Host: Georgia Institute of Technology)

National semifinals and championship (Final Four and championship) March 31 and April 2 Hubert H. Humphrey Metrodome, Minneapolis, Minnesota (Host: University of Minnesota)

Qualifying teams

Automatic bids The following teams were automatic qualifiers for the 2001 NCAA field by virtue of winning their conference's tournament (except for the Ivy League and Pac-10, whose regular-season champions received their automatic bids).

ConferenceSchoolAppearanceLast bidACCDuke25th2000America EastHofstra4th2000Atlantic 10Temple25th2000Big 12Oklahoma20th2000Big EastBoston College12th1997Big SkyCal State Northridge1stNeverBig SouthWinthrop3rd2000Big TenIowa20th1999Big WestUtah State14th2000ColonialGeorge Mason3rd1999C-USACharlotte8th1999Ivy LeaguePrinceton22nd1998MAACIona7th2000MACKent State2nd1999MCCButler5th2000MEACHampton1stNeverMid-ConSouthern Utah1stNeverMissouri ValleyIndiana State3rd2000Mountain WestBYU19th1995NortheastMonmouth2nd1996Ohio ValleyEastern Illinois2nd1992Pac-10Stanford10th2000PatriotHoly Cross9th1993SECKentucky43rd2000SouthernUNC Greensboro2nd1996SouthlandNorthwestern State1stNeverSun BeltWestern Kentucky17th1995SWACAlabama State1stNeverTAACGeorgia State2nd1991WACHawaii3rd1994West CoastGonzaga4th2000

Listed by region and seeding

East Regional – PhiladelphiaSeedSchoolConferenceRecordBerth Type#1 Duke ACC 29–4 Automatic#2 Kentucky SEC 22–9 Automatic#3 Boston College Big East 26–4 Automatic#4 UCLA Pac-10 21–8 At-large#5 Ohio State Big Ten 20–10 At-large#6 USC Pac-10 21–9 At-large#7 Iowa Big Ten 22–11 Automatic#8 Georgia SEC 16–14 At-large#9 Missouri Big 12 19–12 At-large#10 Creighton Missouri Valley 24–7 At-large#11 Oklahoma State Big 12 20–9 At-large#12 Utah State Big West 27–5 Automatic#13 Hofstra America East 26–4 Automatic#14 Southern Utah Mid-Continent 25–5 Automatic#15 Holy Cross Patriot 22–7 Automatic#16 Monmouth NEC 21–9 AutomaticWest Regional – AnaheimSeedSchoolConferenceRecordBerth Type#1 Stanford Pac-10 28–2 Automatic#2 Iowa State Big 12 25–5 At-large#3 Maryland ACC 21–10 At-large#4 Indiana Big Ten 21–12 At-large#5 Cincinnati C-USA 23–9 At-large#6 Wisconsin Big Ten 18–10 At-large#7 Arkansas SEC 20–10 At-large#8 Georgia Tech ACC 17–12 At-large#9 Saint Joseph's Atlantic 10 25–6 At-large#10 Georgetown Big East 23–7 At-large#11 Georgia State TAAC 28–4 Automatic#12 BYU Mountain West 24–8 Automatic#13 Kent State MAC 23–9 Automatic#14 George Mason Colonial 18–11 Automatic#15 Hampton MEAC 24–6 Automatic#16 UNC Greensboro Southern 19–11 Automatic South Regional – AtlantaSeedSchoolConferenceRecordBerth Type#1 Michigan State Big Ten 24–4 At-large#2 North Carolina ACC 25–6 At-large#3 Florida SEC 23–6 At-large#4 Oklahoma Big 12 26–6 Automatic#5 Virginia ACC 20–8 At-large#6 Texas Big 12 25–8 At-large#7 Penn State Big Ten 19–11 At-large#8 California Pac-10 20–10 At-large#9 Fresno State WAC 25–6 At-large#10 Providence Big East 21–9 At-large#11 Temple Atlantic 10 21–12 Automatic#12 Gonzaga WCC 24–6 Automatic#13 Indiana State Missouri Valley 21–11 Automatic#14 Western Kentucky Sun Belt 24–6 Automatic#15 Princeton Ivy League 16–10 Automatic#16 Alabama State SWAC 22–8 Automatic Midwest Regional – San AntonioSeedSchoolConferenceRecordBerth Type#1 Illinois Big Ten 24–7 At-large#2 Arizona Pac-10 23–7 At-large#3 Ole Miss SEC 25–7 At-large#4 Kansas Big 12 24–6 At-large#5 Syracuse Big East 24–8 At-large#6 Notre Dame Big East 19–9 At-large#7 Wake Forest ACC 19–10 At-large#8 Tennessee SEC 19–11 At-Large#9 Charlotte C-USA 21–10 Automatic#10 Butler MCC 23–7 Automatic#11 Xavier Atlantic 10 21–7 At-large#12 Hawaii WAC 17–13 Automatic#13 Cal State Northridge Big Sky 22–9 Automatic#14 Iona MAAC 22–10 Automatic#15 Eastern Illinois Ohio Valley 21–9 Automatic#16 Northwestern State Southland 18–12 Automatic Winthrop Big South 18–12 Automatic

Bids by conference BidsConferenceSchools 7 Big Ten Illinois, Indiana, Iowa, Michigan State, Ohio State, Penn State, Wisconsin 6 ACC Duke, Georgia Tech, Maryland, North Carolina, Virginia, Wake Forest Big 12 Iowa State, Kansas, Missouri, Oklahoma, Oklahoma State, Texas SEC Arkansas, Florida, Georgia, Kentucky, Ole Miss, Tennessee 5 Big East Boston College, Georgetown, Notre Dame, Providence, Syracuse Pac-10 Arizona, California, Stanford, UCLA, USC3 Atlantic 10 Saint Joseph's, Temple, Xavier 2 C-USA Charlotte, Cincinnati Missouri Valley Creighton, Indiana State WAC Fresno State, Hawaii 1 21 other conferences

Bids by conference Bids by ConferenceBidsConference(s) 7 Big Ten 6 ACC, Big 12, SEC 5 Big East, Pac-10 3 Atlantic 10 2C-USA, Missouri Valley, WAC 1 21 others

Final Four At Hubert H. Humphrey Metrodome, Minneapolis, Minnesota

National semifinals March 31, 2001 Duke (E1) 95, Maryland (W3) 84 The fourth meeting of the year between ACC rivals Duke and Maryland – both road teams won during the ACC regular season before Duke won 84–82 in the ACC Tournament semifinals in Atlanta en route to winning the tournament – turned into a classic. Maryland jumped out of the gate to an early 39–17 lead. It appeared the Terps would eliminate Duke, led by senior Shane Battier. However, Duke was able to cut the lead at halftime to 49–38. Duke would take its first lead when Jason Williams drained a three to give Duke the lead 73–72 with 6:48 to play. Duke closed the game with a 23–12 run to stun Gary Williams' Maryland squad. Referees: David Libbey, Mark Reischling, and Ted Hillary. Arizona (M2) 80, Michigan State (S1) 61 In an emotional season in which Arizona coach Lute Olson suffered the loss of his wife Bobbi, he would be just 40 minutes away from a second National Championship after his Wildcats destroyed the defending national champion Michigan State Spartans. The game was close at halftime with Arizona leading by just 2. However, Arizona outscored Michigan State 48–31 in the second half en route to the 19-point victory.

Championship game

April 2, 2001 Duke (E1) 82, Arizona (M2) 72 The second-ranked team coming into the NCAA tournament would leave giving coach Mike Krzyzewski his third National Championship at Duke. Arizona cut Duke's lead to 39–37 early in the second half, but Mike Dunleavy Jr. connected on three three-pointers during an 11–2 Duke run. Dunleavy Jr. led the Duke Blue Devils with 21 points. The Arizona Wildcats would cut the gap to 3 four times, twice inside the four-minute TV timeout. However, Shane Battier proved himself too much for the Wildcats to handle as he hit two critical shots to put the Blue Devils comfortably ahead. Jason Williams, despite a poor shooting night, iced the game with a three-pointer from the top of the key with under 2 minutes to play to give Duke an eight-point lead. The final score was Duke 82 – Arizona 72.

Bracket Opening Round game – Dayton, Ohio Winner advances to 16th seed in Midwest Regional vs. (1) Illinois.

East regional — Philadelphia, Pennsylvania

Ohio State vacated all wins and its NCAA Tournament appearance from the 2000–01 season due to the Jim O’Brien scandal. Unlike forfeiture, a vacated game does not result in the other school being credited with a win, only with Ohio State removing the wins from its own record.

West regional — Anaheim, California

South regional — Atlanta, Georgia

Midwest regional — San Antonio, Texas

Final Four — Minneapolis, Minnesota

Upsets

This tournament featured many upsets in the first two rounds, with pairs of #10, #11, #12, and #13 seeds winning in the first and a #10, #11, and #12 seeds all making it to the Sweet 16. The best remembered and most unexpected occurred when Hampton beat number 2 seed Iowa State 58–57 in the first round. The Pirates were down by as much as 11 in the game and outscored the Cyclones 10–0 in the final seven minutes of the game. Tarvis Williams made the winning shot with 6.9 seconds left. The video of Hampton coach Steve Merfield being lifted in the air by player David Johnson during the celebration has become a classic clip, often played by CBS and ESPN to showcase the excitement of the underdog in the NCAA tournament.

Hampton became only the fourth #15 seed to win a game since the tournament expanded to 64 teams in 1985 and the first since 1997. They went on to lose to Georgetown in the second round, failing to become the first seed that low to make the Round of 16.15th-seeded Pirates stun No. 2 seed Cyclones 58–57 The Pirates were the last #15 seed to advance in the tournament until 2012, in which two #15 seeds beat their #2-seeded opponents.