Yotsuba may refer to: Yotsuba&!, a Japanese manga by Kiyohiko Azuma Yotsuba Koiwai, the title character from Yotsuba&! Yotsuba, a character from the manga and anime Sister Princess Yotsuba Nakano, a character from the manga and anime The Quintessential Quintuplets Yotsuba Group, the name of a group in the Japanese manga and anime Death Note