XPC or xpc may refer to:

Pecheneg language, ISO 639-3 code 'xpc' Shuttle XPC, popular line of barebones computers and cases. SPEC XPC, the X Performance Characterization group working under the SPEC GPC group. Xeroderma pigmentosum, complementation group C, a human gene xPC Target, a product from MathWorks XPC Golf Clubs, a proprietary brand from Golfsmith