The 2006 Stanley Cup playoffs for the National Hockey League (NHL) championship began on April 21, 2006, following the 2005–06 regular season. This was the first playoffs since 2004 due to the 2004–05 NHL lockout that cancelled the previously scheduled season. The 16 teams that qualified, seeded one through eight from each conference, played best-of-seven series with re-seeding after the Conference quarterfinals. The conference champions played a best-of-seven series for the Stanley Cup.

The Finals concluded on June 19 with the Carolina Hurricanes winning the Stanley Cup, defeating the Edmonton Oilers in the final series four games to three. Carolina goaltender Cam Ward was awarded the Conn Smythe Trophy as Most Valuable Player of the playoffs. The Edmonton Oilers would miss the playoffs each year thereafter until 2017. This was also the last time until 2023 that the Pittsburgh Penguins missed the playoffs. The St. Louis Blues missed the playoffs for the first time since 1979, ending a 25-season playoff streak, the third longest in NHL history. The current longest playoff appearance streak in both pro sports and NHL moved to the Detroit Red Wings at 15 consecutive seasons. This was additionally the first time in history that the Chicago Blackhawks and the St. Louis Blues missed the playoffs in the same season.

While the 2005–06 season introduced a shootout to break ties after five minutes of four-on-four overtime, the Stanley Cup playoffs retained their traditional format of unlimited 20-minute periods of five-on-five sudden-death overtime to break ties.

The Western Conference made history in the first round when all four series were won by the lower-seeded teams (conversely, all four series in the Eastern Conference were won by the higher-seeded teams). The eighth- and lowest-seeded Oilers proceeded to win the Western Conference and participate in the Stanley Cup Finals. Four Canadian teams qualified for the playoffs this year, this total was not equaled again until 2013 and not exceeded until 2015 with five.

Playoff seeds The top eight teams in each conference qualified for the playoffs. The top three seeds in each conference were awarded to the division winners; while the five remaining spots were awarded to the highest finishers in their respective conferences.

The following teams qualified for the playoffs:

Eastern Conference Ottawa Senators, Northeast Division champions, Eastern Conference regular season champions – 113 points Carolina Hurricanes, Southeast Division champions – 112 points New Jersey Devils, Atlantic Division champions – 101 points (46 wins) Buffalo Sabres – 110 points Philadelphia Flyers – 101 points (45 wins) New York Rangers – 100 points Montreal Canadiens – 93 points Tampa Bay Lightning – 92 points

Western Conference Detroit Red Wings, Central Division champions, Western Conference regular season champions, Presidents' Trophy winners – 124 points Dallas Stars, Pacific Division champions – 112 points Calgary Flames, Northwest Division champions – 103 points Nashville Predators – 106 points San Jose Sharks – 99 points Mighty Ducks of Anaheim – 98 points Colorado Avalanche – 95 points (43 wins) Edmonton Oilers – 95 points (41 wins)

Playoff bracket In each round, teams competed in a best-of-seven series following a 2–2–1–1–1 format (scores in the bracket indicate the number of games won in each best-of-seven series). The team with home ice advantage played at home for games one and two (and games five and seven, if necessary), and the other team played at home for games three and four (and game six, if necessary). The top eight teams in each conference made the playoffs, with the three division winners seeded 1–3 based on regular season record, and the five remaining teams seeded 4–8.

The NHL used "re-seeding" instead of a fixed bracket playoff system. During the first three rounds, the highest remaining seed in each conference was matched against the lowest remaining seed, the second-highest remaining seed played the second-lowest remaining seed, and so forth. The higher-seeded team was awarded home ice advantage. The two conference winners then advanced to the Stanley Cup Finals, where home ice advantage was awarded to the team that had the better regular season record.

Conference quarterfinals

Eastern Conference quarterfinals

(1) Ottawa Senators vs. (8) Tampa Bay Lightning

The Ottawa Senators entered the playoffs as the Eastern Conference regular season and Northeast Division champions with 113 points. Tampa Bay qualified as the eighth seed earning 92 points during the regular season. This was the first playoff meeting between these two teams. Ottawa won all four games during this year's regular season series.

The Senators defeated the Lightning in five games. The Senators used a two-man advantage in the third period of game one to gain the lead as they took the game by a score of 4–1. In game two the Lightning came back from a one-goal deficit by scoring two goals 55 seconds apart as they evened the series with a 4–3 victory. Six Ottawa skaters scored a goal in game three as the Senators won 8–4. Ottawa scored three times in the second-period of game four as they earned a 5–2 win. Martin Havlat scored the series-winning goal for the Senators at 15:02 of the second period as Ottawa closed out the series with a 3–2 victory.

(2) Carolina Hurricanes vs. (7) Montreal Canadiens

The Carolina Hurricanes entered the playoffs as the Southeast Division champions, earning the second seed in the Eastern Conference with 112 points. Montreal qualified as the seventh seed earning 93 points during the regular season. This was the seventh playoff meeting between these two teams with Montreal winning five of the six previous series. They last met in the 2002 Eastern Conference semifinals where Carolina won in six games. Carolina won all four games during this year's regular season series.

The Hurricanes eliminated the Canadiens in six games. After allowing a goal in the opening minute of game one the Canadiens scored six unanswered goals taking the opening game of the series 6–1. Carolina pulled goaltender Martin Gerber after allowing three goals in the first period of game two and he was replaced by 22-year-old rookie backup Cam Ward. The Hurricanes were able to tie the game with 90 seconds remaining in regulation before losing in double overtime as Michael Ryder scored at 2:32, giving Montreal a 6–5 win. In game three Eric Staal scored the game winner 3:38 into overtime as Carolina won 2–1. Rod Brind'Amour gave the Hurricanes the lead in game four and they hung on to win 3–2. Cam Ward made 30 saves and allowed just one goal against as the Hurricanes took game five 2–1. Hurricanes forward Cory Stillman ended the series at 1:19 of the first overtime as Carolina won game six 2–1.

(3) New Jersey Devils vs. (6) New York Rangers

The New Jersey Devils entered the playoffs as the Atlantic Division champions (winning the tie-breaker with Philadelphia in total wins), earning the third seed in the Eastern Conference with 101 points. New York qualified for the first time since 1997 as the sixth seed earning 100 points during the regular season. This was the fourth playoff meeting between these two teams with New York winning all three previous series. They last met in the 1997 Eastern Conference semifinals where New York won in five games. The teams split this year's eight game regular season series.

The Devils swept the Rangers in four games. The Devils scored five times on the power play in game one winning 6–1, Devils forward Patrik Elias scored six points in the victory (two goals and four assists). In game two John Madden scored a hat trick for the Devils as they earned a 4–1 victory. Martin Brodeur earned his 21st career playoff shutout with 25 saves as the Devils won game three 3–0. New Jersey took the lead in the second period of game four with two power play goals and they never looked back eliminating the Rangers by a final score of 4–2.

(4) Buffalo Sabres vs. (5) Philadelphia Flyers

The Buffalo Sabres entered the playoffs as the fourth seed in the Eastern Conference with 110 points. Philadelphia qualified as the fifth seed (losing the tie-breaker with New Jersey in total wins for the Atlantic Division title) earning 101 points during the regular season. This was the eighth playoff meeting between these two teams with Philadelphia winning five of the seven previous series. They last met in the 2001 Eastern Conference quarterfinals where Buffalo won in six games. Buffalo won three of the four games during this year's regular season series.

The Sabres defeated the Flyers in six games. Philadelphia goaltender Robert Esche made 55 saves in a 3–2 Flyers loss; Daniel Briere ended the game with a goal at 7:31 in double-overtime. Buffalo forwards Jean-Pierre Dumont and Jason Pominville each recorded hat-tricks in game two as the Sabres scored three power play goals rolling to an 8–2 victory. Peter Forsberg scored two second period goals in game three to break a 1–1 tie, the Flyers went on to win the game 4–2. In game four R. J. Umberger put the Flyers up for good with his goal at 9:51 in the third period as Philadelphia evened the series with a 5–4 victory. Sabres goaltender Ryan Miller made 24 saves to earn his first career playoff shutout in game five as Buffalo won 3–0. In game six the Sabres jumped to a 5–0 lead on a goal by Maxim Afinogenov as the Flyers pulled Robert Esche from the game, Buffalo went on to a resounding 7–1 series-clinching victory.

Western Conference quarterfinals

(1) Detroit Red Wings vs. (8) Edmonton Oilers

The Detroit Red Wings entered the playoffs as the Presidents' Trophy winners, the Western Conference regular season and Central Division champions, with 124 points. Edmonton qualified as the eighth seed earning 95 points (losing the tie-breaker with Colorado in total wins) during the regular season. This was the third playoff meeting between these two teams with Edmonton winning both previous series. They last met in the 1988 Clarence Campbell Conference Final where Edmonton won in five games. Detroit won this year's four game regular season series earning six of eight points during the season.

The eighth seeded Oilers upset the Red Wings in six games. Red Wings winger Kirk Maltby scored two goals in game one, including the winner in double overtime as Detroit won 3–2. The Oilers took the lead by scoring twice in 57 seconds in the second period of game two as they hung on to win 4–2. Jarret Stoll provided the game-winner in double overtime in game three giving the Oilers a 4–3 victory. The Red Wings scored three power-play goals in game four earning a 4–2 victory to tie the series. Oilers goaltender Dwayne Roloson made 30 saves as Edmonton hung on to win game five by a score of 3–2. The Oilers overcame a two-goal deficit after two periods of play in game six by scoring four times in third period, and Ales Hemsky broke the tie with 1:06 remaining in regulation as Edmonton ended the series with a 4–3 win.

(2) Dallas Stars vs. (7) Colorado Avalanche

The Dallas Stars entered the playoffs as the Pacific Division champions, earning the second seed in the Western Conference with 112 points. Colorado qualified as the seventh seed earning 95 points (winning the tie-breaker with Edmonton in total wins) during the regular season. This was the fourth and 2nd most recent playoff meeting between these two teams, with Dallas winning two of three previous series. They last met in the 2004 Western Conference quarterfinals where Colorado won in five games.