Fludiazepam, US Patent 3371085 5-aryl-3h-1,4-benzodiazepin-2(1h)-ones marketed under the brand name Erispan (エリスパン) is a potent benzodiazepine and 2ʹ-fluoro derivative of diazepam, originally developed by Hoffmann-La Roche in the 1960s.US Patent 3299053 -ARYL-JH-L,X-BENZODIAZEPIN-Z(LH)-ONES It is marketed in Japan and Taiwan. It exerts its pharmacological properties via enhancement of GABAergic inhibition. Fludiazepam has 4 times more binding affinity for benzodiazepine receptors than diazepam. It possesses anxiolytic, anticonvulsant, sedative, hypnotic and skeletal muscle relaxant properties. Fludiazepam has been used recreationally.
See also 2′-Bromonordazepam Diazepam Diclazepam (the 2ʹ-chloro analog) Difludiazepam (the 2',6'-difluoro derivative) Flunitrazepam (the 7-nitro analog) Flualprazolam (the triazolo derivative) Flutemazepam (the 3-hydroxy analog) Ro20-8552
References
External links
Official Dainippon Sumitomo Pharma Website