Mohammad Saiful Islam Khan () (born 14 April 1969) is a former Bangladeshi cricketer who played in seven One Day Internationals from 1990 to 1997.

Originally from Mymensingh, Saif played for the Bangladesh U-19 side in 1989.: Rafiqul Ameer."Looking Back: Bangladesh Cricket in the 80's". Retrieved on 2007-12-18. He made his full ODI debut at Eden Gardens, Calcutta, on 31 December 1990. His best performance in ODI came at Sharjah against Sri Lanka in 1995. He took 4/36 to help Bangladesh bowl out their opposition for the first time in a full ODI. He also played in the Bangladesh side that won the ICC Trophy in 1997. But with the emergence of a group of talented medium pacers, he soon lost his place in the national side.

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