John Prentice may refer to:
John Prentice (businessman), chairman of the Shanghai Municipal Council John Prentice (cartoonist) John Prentice (footballer, born 1898) John Prentice (footballer, born 1926) John Rockefeller Prentice (1902–1972), lawyer John Prentice, fictional character played by Sidney Poitier in the 1967 film Guess Who's Coming to Dinner
See also John Prentis, mayor of Williamsburg, Virginia John Holmes Prentiss, U.S. Representative