Kunene or Cunene may refer to:
Geography Kunene River (also spelled Cunene), Angola and Namibia Kunene Region, Namibia Cunene Province, Angola
People Daniel Kunene (1923–2016), South African literary scholar, translator and writer Dominic Kunene, Liswati football manager Kenny Kunene (born 1970), South African businessman Manqoba Kunene (born 1982), Liswati footballer Madala Kunene (born 1947), South African musician Mazisi Kunene (1930–2006), South African poet and historian Ntandoyenkosi Kunene, South African beauty pageant contestant Victor Kunene (born 1966), South African boxer