KTTS may refer to:
The ICAO airport code for NASA Shuttle Landing Facility KTTS-FM, a radio station (94.7 FM) licensed to Springfield, Missouri, United States KGMY, a radio station (1400 AM) licensed to Springfield, Missouri, United States which held the call sign KTTS from 1926 to 1987 KOLR, a television station (channel 10) licensed to Springfield, Missouri, United States which held the call sign KTTS-TV from 1953 to 1971 KDE Text-to-speech engine