Clerke may refer to:
Clerke (surname) .38/.45 Clerke, a wildcat semi-automatic pistol cartridge Clerke (crater), a lunar crater named after Agnes Mary Clerke Clerke Rocks, a group of small rocky islands in the South Atlantic, named after Charles Clerke Clerke v. Harwood (1797), a United States Supreme Court case concerning debts owed to British subjects
See also Clark (disambiguation) Clarke (disambiguation) Clerk (disambiguation)