A43 or A-43 may refer to:
Military Curtiss A-43 Blackhawk, an American prototype aircraft Douglas A-43 Jetmaster, an American prototype aircraft Black Prince (tank), an experimental British heavy tank
Advanced Landing Ground A-43, an airfield in France
Roads A43 road, a primary road in the English Midlands A43 road (Northern Ireland), a primary road in Northern Ireland A43 autoroute, a French highway A 43, Bundesautobahn 43 in Germany
Other uses HLA-A43, an HLA-A serotype Benoni Defense, a chess opening (by Encyclopaedia of Chess Openings code)