Eastern spadefoot or eastern spadefoot toad may refer to:

Scaphiopus holbrookii or eastern spadefoot, a toad found in North America Pelobates syriacus or eastern spadefoot, a toad found in Eastern Europe and the Middle East Eastern spadefoot toads (Leptobrachium), a genus of Southeast Asian toads, from family Megophryidae, unrelated to the above species