Gamez or Gámez is a Spanish-language surname. Notable people with the name include:
Ana Patricia Gámez (born 1987), Mexican beauty queen Blanca Amelia Gámez (born 1950), Mexican politician Celia Gámez (1905–1992), Argentine actress and dancer Eduardo Gámez (born 1991), professional Mexican footballer Elisbet Gámez (born 1997), Cuban swimmer Enrique Gámez (born 1981), Ecuadorian footballer Fran Gámez (born 1991), Spanish footballer Francisca Rubio Gámez (born 1949), aka Fanny Rubio, Spanish professor and writer (1943–1984), Peruvian professor and founder of SUTEP Jesús Gámez (born 1985), Spanish professional footballer José Luis Íñiguez Gámez (born 1978), a Mexican politician from the National Action Party Juan de Alfaro y Gamez (1610–1680), Spanish Baroque painter Juan José Gámez (1939–1997), Costa Rican football player and manager Julio César Gámez Interiano (born 1955), Honduran politician Leo Gamez, Silvio Rafael Gamez, (born 1963), Venezuelan boxer Máximo Gámez (born 1989), Nicaraguan professional defender Melany Bergés Gámez (born 1990), blind Spanish Paralympic athlete Miguel Ángel Gámez (born 1954), Honduran politician Oscar Serrano-Gamez or Óscar Serrano (tennis) (born 1978), former Spanish professional male tennis player Rafael Muino Gamez (born 1975), Spanish wheelchair basketball player Robert Gamez (born 1968), American professional golfer Roberto Gámez Panchamé (born 1950), Honduran veterinarian and politician Victoria Gamez (1923–2005), Spanish operatic lyric soprano and recitalist