Wu Chen may refer to:
People with surname Wǔ 武 Wu Chen (general) (?–208 BCE, 武臣), rebel of Qin dynasty, prior to Chu–Han Contention
People with surname Wú 吳 Wu Chen, Prince of Changsha (3rd century–193 BCE, 吳臣), vassal-prince of Changsha of Han dynasty, son of Wu Rui
See also Wu Cheng (disambiguation) Wu Zhen (disambiguation)