Siegenthaler is a surname. Notable people with the surname include:
Bernard Siegenthaler, Swiss sports shooter Fritz Siegenthaler (born 1929), Swiss cyclist Hans Siegenthaler (1923–2007), Swiss footballer John Seigenthaler (1927–2014), American journalist John Seigenthaler (anchorman) (born 1955), son of the journalist Jonas Siegenthaler (born 1997), Swiss ice hockey player Maja Siegenthaler (born 1992), Swiss competitive sailor Sina Siegenthaler (born 2000), Swiss snowboarder Therese Siegenthaler (1953–1974), Swiss student, one of the victims of the serial killers Fred and Rose West Urs Siegenthaler (born 1947), Swiss footballer
See also Seigenthaler, surname